Publications

what we write

Click here to see a list of publications on PubMed.

2018

Protection of tissue physicochemical properties using polyfunctional crosslinkers.

Park YG, Sohn CH, Chen R, McCue M, Yun DH, Drummond GT, Ku T, Evans NB, Oak HC, Trieu W, Choi H, Jin X, Lilascharoen V, Wang J, Truttmann MC, Qi HW, Ploegh HL, Golub TR, Chen SC, Frosch MP, Kulik HJ, Lim BK, Chung K.

Nat Biotechnol. 2018 Dec 17. doi: 10.1038/nbt.4281. [Epub ahead of print]

PMID: 30556815


Chaperone AMPylation modulates aggregation and toxicity of neurodegenerative disease-associated polypeptides.

Truttmann MC, Pincus D, Ploegh HL.

Proc Natl Acad Sci U S A. 2018 May 29;115(22):E5008-E5017. doi: 10.1073/pnas.1801989115. Epub 2018 May 14.

PMID: 29760078


2017

In vitro AMPylation Assays Using Purified, Recombinant Proteins.

Truttmann MC, Ploegh HL.

Bio Protoc. 2017 Jul 20;7(14). pii: e2416. doi: 10.21769/BioProtoc.2416.

PMID: 29170749


Site-Specific Protein Labeling via Sortase-Mediated Transpeptidation.

Antos JM, Ingram J, Fang T, Pishesha N, Truttmann MC, Ploegh HL.

Curr Protoc Protein Sci. 2017 Aug 1;89:15.3.1-15.3.19. doi: 10.1002/cpps.38.

PMID: 28762490


rAMPing Up Stress Signaling: Protein AMPylation in Metazoans.

Truttmann MC, Ploegh HL.

Trends Cell Biol. 2017 Aug;27(8):608-620. doi: 10.1016/j.tcb.2017.03.004. Epub 2017 Apr 19. Review.

PMID: 28433487


Hepta-Mutant Staphylococcus aureus Sortase A (SrtA7m) as a Tool for in Vivo Protein Labeling in Caenorhabditis elegans.

Wu Q, Ploegh HL, Truttmann MC.

ACS Chem Biol. 2017 Mar 17;12(3):664-673. doi: 10.1021/acschembio.6b00998. Epub 2017 Jan 18.

PMID: 28098972


Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response.

Truttmann MC, Zheng X, Hanke L, Damon JR, Grootveld M, Krakowiak J, Pincus D, Ploegh HL.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E152-E160. doi: 10.1073/pnas.1619234114. Epub 2016 Dec 28.

PMID: 28031489


2016

Recent advances in sortase-catalyzed ligation methodology.

Antos JM, Truttmann MC, Ploegh HL.

Curr Opin Struct Biol. 2016 Jun;38:111-8. doi: 10.1016/j.sbi.2016.05.021. Epub 2016 Jun 16. Review.

PMID: 27318815


The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones.

Truttmann MC, Cruz VE, Guo X, Engert C, Schwartz TU, Ploegh HL.

PLoS Genet. 2016 May 3;12(5):e1006023. doi: 10.1371/journal.pgen.1006023. eCollection 2016 May.

PMID: 27138431


Corrigendum: Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.

Maruyama T, Dougan SK, Truttmann MC, Bilate AM, Ingram JR, Ploegh HL.

Nat Biotechnol. 2016 Feb;34(2):210. doi: 10.1038/nbt0216-210c. No abstract available.

PMID: 26849523


2015

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.

Maruyama T, Dougan SK, Truttmann MC, Bilate AM, Ingram JR, Ploegh HL.

Nat Biotechnol. 2015 May;33(5):538-42. doi: 10.1038/nbt.3190. Epub 2015 Mar 23. Erratum in: Nat Biotechnol. 2016 Feb;34(2):210.

PMID: 25798939


HypE-specific nanobodies as tools to modulate HypE-mediated target AMPylation.

Truttmann MC, Wu Q, Stiegeler S, Duarte JN, Ingram J, Ploegh HL.

J Biol Chem. 2015 Apr 3;290(14):9087-100. doi: 10.1074/jbc.M114.634287. Epub 2015 Feb 12.

PMID: 25678711


2014

Simultaneous analysis of large-scale RNAi screens for pathogen entry.

Rämö P, Drewek A, Arrieumerlou C, Beerenwinkel N, Ben-Tekaya H, Cardel B, Casanova A, Conde-Alvarez R, Cossart P, Csúcs G, Eicher S, Emmenlauer M, Greber U, Hardt WD, Helenius A, Kasper C, Kaufmann A, Kreibich S, Kühbacher A, Kunszt P, Low SH, Mercer J, Mudrak D, Muntwiler S, Pelkmans L, Pizarro-Cerdá J, Podvinec M, Pujadas E, Rinn B, Rouilly V, Schmich F, Siebourg-Polster J, Snijder B, Stebler M, Studer G, Szczurek E, Truttmann M, von Mering C, Vonderheit A, Yakimovich A, Bühlmann P, Dehio C.

BMC Genomics. 2014 Dec 22;15:1162. doi: 10.1186/1471-2164-15-1162.


2013

Bartonella henselae trimeric autotransporter adhesin BadA expression interferes with effector translocation by the VirB/D4 type IV secretion system.

Lu YY, Franz B, Truttmann MC, Riess T, Gay-Fraret J, Faustmann M, Kempf VA, Dehio C.

Cell Microbiol. 2013 May;15(5):759-78. doi: 10.1111/cmi.12070. Epub 2012 Dec 6.

PMID: 23163798


2011

Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake.

Truttmann MC, Misselwitz B, Huser S, Hardt WD, Critchley DR, Dehio C.

J Cell Sci. 2011 Nov 1;124(Pt 21):3591-602. doi: 10.1242/jcs.084459. Epub 2011 Nov 1.

PMID: 22045736


BID-F1 and BID-F2 domains of Bartonella henselae effector protein BepF trigger together with BepC the formation of invasome structures.

Truttmann MC, Guye P, Dehio C.

PLoS One. 2011;6(10):e25106. doi: 10.1371/journal.pone.0025106. Epub 2011 Oct 17.

PMID: 22043280


Combined action of the type IV secretion effector proteins BepC and BepF promotes invasome formation of Bartonella henselae on endothelial and epithelial cells.

Truttmann MC, Rhomberg TA, Dehio C.

Cell Microbiol. 2011 Feb;13(2):284-99. doi: 10.1111/j.1462-5822.2010.01535.x. Epub 2010 Oct 22.

PMID: 20964799


2009

A translocated protein of Bartonella henselae interferes with endocytic uptake of individual bacteria and triggers uptake of large bacterial aggregates via the invasome.

Rhomberg TA, Truttmann MC, Guye P, Ellner Y, Dehio C.

Cell Microbiol. 2009 Jun;11(6):927-45. doi: 10.1111/j.1462-5822.2009.01302.x. Epub 2009 Feb 27.

PMID: 19302579